Its first image analyzer 4x'd our usage
Sophie 3 (beta)
The third Sophie added text analysis and the first iteration of CLYTE's image analyzer, which turns scratch assay images into gap % numbers.
LOG · WHAT IT IS AND WHAT IT DOES
Sophie is CLYTE's AI lab assistant: it helps you make detailed SOPs for your cell lab experiments, troubleshoot issues, and learn new assays. Sophie 3 added text analysis and the first iteration of our image analyzer for scratch (cell migration) assays, which 4x'd our usage. This first version would take the T1 and T2 images and give you the gap % numbers.
WHY
It came out of feedback from talking to people at TERMIS-AM 25, where people asked for more analysis functions. It also built on the existing infrastructure, making it faster and more efficient as I learned more tricks for developing AI engines, and we extended the SOP context database too.
WHAT I WORKED ON
Again the full stack, now with the new vision engine.
WHAT CAME OF IT
Everything until Sophie 4.5 was a public beta, just eating the cost and learning from users. We learned people want more analysis. We also studied people's usage and saw many users copying the gap numbers into the main Sophie chat engine, to have it analyze the migration and interpret the results. That led to the improvements in versions 4 and 4.5.
- OBJECT
- M34
- YEAR
- 2026
- CONTEXT
- CLYTE
- CATEGORY
- work
- TYPE
- software
- STATE
- out in the world
- TOPICS
PLATES · 4
PLATE IThe Scratch Analyzer, T1 and T2 images in
PLATE IIAnalysis complete, with an Excel report
PLATE IIIThe chat, ready for a question
PLATE IVA scratch assay protocol, section by section
DEMO · 1
Stop Using ImageJ for Cell Migration (Do This Instead)ON YOUTUBE
SOPHIE SERIES
- Sophie 1 (beta) · 2025
- Sophie 3 (beta) · 2026
- Sophie 4.5 · 2026
- Sophie 5.0 · 2026
- Gemini XPRIZE: Top 100 · 2026
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